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However, the safety and effectiveness of CRESTOR were evaluated in a two year open-label uncontrolled trial that included children and adolescents 8 to 17 years of age with heterozygous familial hypercholesterolemia crestor [see Clinical Studies] . CRESTOR has not been studied in controlled clinical trials involving prepubertal patients or patients younger than 10 years of age crestor with heterozygous familial hypercholesterolemia . The safety and efficacy of CRESTOR in lowering LDL-C appeared generally consistent with that observed crestor for adult patients, despite limitations of the uncontrolled study design .
Table 3: Adverse Reactions* Reported in ? 2% of Patients Treated with CRESTOR and > Placebo crestor in the JUPITER Trial (% of Patients ) .


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